Semaglutide is o FDA approved injectable glucagon-like peptide-l (GIP-1) agonist that’s administered once weekly for weight loss. GLp-t is an incretin hormone that plays a role in appetite and digestion. Incretin hormones released by your small intestine are sent out by your body after you’ve eaten a meal to help lower blood sugar by triggering insulin and blocking other sources of sugar. It also slows down how quickly food leaves your stomach (called gastric emptying). This results in feeling filer longer- lowering your appetite causing you to lose weight.